You didn't say what the intended application might be, but lets assume an all around wide range powerhouse, and not strictly drag racing.
This is just my opinion now... it can be easily done...
JR Motorsports 109H (hardened nitrided solid) cam, and good Comp or Crower lifters with oiling hole in the face. Yes, this is a circle track camshaft, but everyone knows that circle track cams give the most low and mid-range torque and usable horsepower, this one 3000 thru 7600.
If going with steel heads, Dart Platinum II 215 or 230 with 2.06 1.55 minimum, or World Products Sportsman II with same.
Intake - Edelbrock Super Victor, or Hurricane tall.
Carb - Pro System SV1, Braswell, ProForm Quick Fuel, or possibly the new Holley HP hybrid (I haven't tried one yet?), 750 to 850 depending on application.
This is what most dirt car builders are using with your specified bottom end, and we are making 500+ wide range power every time...
Again, just my opinion... take it for what its worth.