I used run a 10-bolt from a mid 70's camaro using a 10" wide wheel and 7.5" of backspacing the wheels will stick out a little.. I have also heard that you can drop in an 8.8 out of an explorer basically the same width as a stock S10..
I am still running the same rearend in the truck pictured below just had it narrowed 6 3/4" with the same wheels..15x10 with 7.5" BS