Engine configuration can definately affect how the carb reacts on it. The big part is getting the carb tuned properly for the engine it's on. While there are countless racers out there that run out of the box carbs and do well, or use a buddy's carb and run well, it's also a well known fact that alot of the carbs out there are way out of calibration and can see substantial improvement when properly tuned to the engine they are being used on. Best of luck, let me know who things go!