Is the master higher than the calipers?If it is mounted real low(under the floor board...)the fluid will drain back to the master and you will have to pump it back out to stop.Been there before myself

Also make sure you use residual valves.Basically a one way check valve.Disce require the 10 psi res valves.That might help too.And ,no the line lock won't affect you,or need bleeding.It's only function is to valve off the line to hold the fluid pressure until you release it,then it's wide open.That won't be your problem.